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December 7, 2007Colorectal DiseaseOpen Access

The management and outcome of anastomotic leaks in colorectal surgery

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Why the study?

Does early and aggressive management improve outcomes in patients with anastomotic leaks following colorectal surgery?

Population

Patients with anastomotic leaks following colorectal surgery

Design

Review

Authors

AKAadil KhanUniversity of ChicagoJWJ. M. D. WheelerOxfamCCChris CunninghamCalifornia Polytechnic State University

Discussion

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Member takes

Overview

Supports early aggressive management to limit mortality in anastomotic leaks; leaves open strategies to reduce permanent stoma risk after takedown.

Structured PICO

Does early and aggressive management improve outcomes in patients with anastomotic leaks following colorectal surgery?

P
Population
Patients with anastomotic leaks following colorectal surgery
I
Intervention
Early and aggressive management
O
Outcome
Mortality and stoma formationhard clinical

Early aggressive management of anastomotic leaks in colorectal surgery is associated with low mortality but high risk of permanent stoma if the anastomosis is taken down.

Cite This Study

Khan et al. (2007) studied this question.

synapsesocial.com/papers/69da7fce387cf70698686d19https://doi.org/10.1111/j.1463-1318.2007.01417.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anterior resection without a defunctioning colostomy: questions of safety1992 · 128 citations
  2. 2Anastomotic leakage after curative anterior resection results in a higher prevalence of local recurrence2003 · 322 citations
  3. 3Anastomotic integrity after operations for large-bowel cancer: a multicentre study.1980 · 503 citations
  4. 4Systematic review of the definition and measurement of anastomotic leak after gastrointestinal surgery2001 · 730 citations
  5. 5Clinical and Subclinical Leaks After Low Colorectal Anastomosis: A Clinical and Radiologic Study2006 · 134 citations