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June 2, 2021Annals of Pharmacotherapy

Impact of Interferons and Biological Drug Inhibitors of IL-2 and IL-6 on Small-Molecule Drug Metabolism Through the Cytochrome P450 System

C Michael White Dakota Sicignano Kimberly Smith

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Abstract

Interferon therapy or inflammatory suppression via IL-2 or IL-6 can alter steady-state concentrations of CYP-metabolized small-molecule drugs.

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White et al. (2021) studied this question.

synapsesocial.com/papers/69da8150a6045d71bfa3cf3e https://doi.org/10.1177/10600280211022281

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