Why the study?
Are circulating levels of sTNFR1 and sTNFR2 associated with infarct size and LV dysfunction in STEMI patients?
Population
STEMI patients
Design
Cohort
Authors
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Hypothesis-generating for TNF pathways in STEMI remodeling; requires prospective validation before clinical adoption.
Are circulating levels of sTNFR1 and sTNFR2 associated with infarct size and LV dysfunction in STEMI patients?
Circulating levels of sTNFR1 and sTNFR2 correlate with infarct size and LV dysfunction in STEMI patients, supporting the role of apoptosis in ischemia-reperfusion injury.
Nilsson et al. (2013) studied this question.
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