Why the study?
Does aprotinin increase the risk of serious end-organ damage compared to aminocaproic acid and tranexamic acid in patients undergoing cardiac surgery?
Population
Patients undergoing cardiac surgery
Comparison
Aprotinin vs Aminocaproic acid and tranexamic acid
Design
Editorial
Authors
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Aprotinin is associated with serious end-organ damage in cardiac surgery, and safer alternatives like aminocaproic acid and tranexamic acid should be used instead.
Does aprotinin increase the risk of serious end-organ damage compared to aminocaproic acid and tranexamic acid in patients undergoing cardiac surgery?
Aprotinin is associated with serious end-organ damage in cardiac surgery, and safer alternatives like aminocaproic acid and tranexamic acid should be used instead.
Mangano et al. (2006) studied this question.
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