Does Percutaneous Coronary Intervention (PCI) improve angina symptom score in patients with stable angina who are receiving little or no antianginal medication and have objective evidence of ischemia?
PCI improves angina symptom scores compared to a placebo procedure in patients with stable angina on minimal antianginal therapy.
Among patients with stable angina who were receiving little or no antianginal medication and had objective evidence of ischemia, PCI resulted in a lower angina symptom score than a placebo procedure, indicating a better health status with respect to angina. (Funded by the National Institute for Health and Care Research Imperial Biomedical Research Centre and others; ORBITA-2 ClinicalTrials.gov number, NCT03742050.).
The ORBITA-2 trial, published in the New England Journal of Medicine, demonstrated that PCI is more effective than a placebo procedure in relieving angina in patients with stable angina who are not on antianginal medication. This has reignited the debate about the role of PCI in stable ischemic heart disease.
Rajkumar et al. (Sat,) studied this question.