Why the study?
Does treatment with ACEIs or ARBs reduce mortality or the need for surgery in patients with abdominal aortic aneurysms?
Does treatment with ACEIs or ARBs reduce mortality or the need for surgery in patients with abdominal aortic aneurysms?
In patients with abdominal aortic aneurysms, ACEI or ARB use is associated with reduced mortality but does not appear to reduce the need for AAA surgery.
Should not change AAA management; leaves open mortality benefit for randomized confirmation.
In this observational study, treatment with ACEIs or ARBs was associated with a comparable reduction in mortality but not in surgery for AAA among patients with AAA. Randomized controlled trials are warranted to confirm these findings.
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Kristensen et al. (2015) studied this question.
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