March 4, 2009

A Population Pharmacokinetic Meta-analysis of Sunitinib Malate (SU11248) and Its Primary Metabolite (SU12662) in Healthy Volunteers and Oncology Patients

Key Points

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Abstract

The magnitude of the predicted changes in exposure with the covariates studied minimizes the necessity for dose adjustment in any of these subpopulations.

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Houk et al. (Wed,) studied this question.

synapsesocial.com/papers/69daaf8685037e71b2684983 https://doi.org/https://doi.org/10.1158/1078-0432.ccr-08-1893

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