Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 10, 2021Nature CommunicationsOpen Access

Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance

View Full Paper
Ask AI
Bookmark
Share

Authors

CYChisato M. YamazakiBrown FoundationAYAiko YamaguchiThe University of Texas MD Anderson Cancer CenterYAYasuaki AnamiBioBridges (United States)

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Yamazaki et al. (2021) studied this question.

synapsesocial.com/papers/69daaff44a1e15904c835b10https://doi.org/10.1038/s41467-021-23793-7
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate2004 · 1,255 citations
  2. 2Engagement of immune effector cells by trastuzumab induces HER2/ERBB2 downregulation in cancer cells through STAT1 activation2014 · 63 citations
  3. 3Intrinsic and Acquired Resistance to HER2-Targeted Therapies in HER2 Gene-Amplified Breast Cancer: Mechanisms and Clinical Implications2012 · 390 citations
  4. 4Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation2011 · 455 citations
  5. 5A NovelSMAD4Mutation Causing Severe Juvenile Polyposis Syndrome with Protein Losing Enteropathy, Immunodeficiency, and Hereditary Haemorrhagic Telangiectasia2015 · 22 citations