Does pharmacomechanical catheter-directed thrombolysis with the Bashir endovascular catheter and low-dose tPA improve RV/LV diameter ratio in patients with intermediate-risk acute pulmonary embolism?
Pharmacomechanical catheter-directed thrombolysis using the Bashir catheter and low-dose tPA effectively reduces RV/LV diameter ratio and pulmonary artery obstruction with a favorable safety profile in intermediate-risk acute PE.
PM-CDT with the Bashir endovascular catheter is associated with a significant reduction in RV/LV diameter ratio and a very low rate of adverse events or major bleeding in patients with intermediate-risk acute PE. The notable finding was a significant reduction in PA obstruction with low-dose tPA. (Recombinant tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden RESCUE; NCT04248868).
Bashir et al. (Sat,) studied this question.
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