Why the study?
Does 12 weeks of endurance exercise training attenuate age-induced increases in remodeling, apoptosis, and Bax/Bcl-2 ratio in the aging rat heart?
Population
Aging rats
Comparison
12 weeks of endurance exercise training vs Age-matched sedentary group
Design
Preclinical
Follow-up
12 weeks
Authors
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Supports exercise-mediated cardioprotection in aging rat hearts; hypothesis-generating for human translation.
Does 12 weeks of endurance exercise training attenuate age-induced increases in remodeling, apoptosis, and Bax/Bcl-2 ratio in the aging rat heart?
Endurance exercise training provides significant protection against age-induced cardiac remodeling and apoptosis in the rat heart.
Kwak et al. (2006) studied this question.
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