Answers are grounded in this paper and cite their sources.
Human bladder 5637 cells cultivated under microgravity conditions formed organoids that displayed characteristics of in vivo tissue-specific differentiation. Uropathogenic Escherichia coli (UPEC) strain CP9 colonized and penetrated the organoids and induced alpha-hemolysin-mediated exfoliation of uroepithelial cells. We propose these uro-organoids as models that simulate the interactions between UPEC and terminally differentiated human urothelium.
No takes yet. Share an insight, caveat, or question.
Smith et al. (2005) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: