Cohort study reveals guideline nonadherence and prolonged infection drive mortality in candidemia, highlighting the crucial need for upfront echinocandin therapy.
Persistent candidemia was predicted by poor adherence to treatment guidelines, as shown by low EQUAL Candida Scores, particularly due to the lack of initial echinocandin use. After controlling immortal time bias, persistent candidemia ≥5 days and ICU admission remained independent predictors of mortality in the multivariable model.
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Sedik et al. (2025) studied this question.
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