A facile and efficient method for the α-trifluoromethylation of carbonyl compounds and enolsilanes has been accomplished through application of a photoredox catalysis strategy. A one-flask procedure for the direct α-trifluoromethylation and α-perfluoroalkylation of ketone, amide, and ester substrates as well as silylketene acetals is described (see scheme).
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Pham et al. (2011) studied this question.
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