Why the study?
Does deep sedation increase mortality and lengths of stay in mechanically ventilated patients?
Does deep sedation increase mortality and lengths of stay in mechanically ventilated patients?
Deep sedation in mechanically ventilated patients is associated with worse outcomes, including increased mortality and longer lengths of stay.
Answers are grounded in this paper and cite their sources.
May support lighter sedation protocols in ventilated ICU patients; leaves open need for larger homogeneous trials.
Deep sedation in mechanically ventilated patients, as evaluated in a small number of qualifying heterogeneous randomized controlled trials and observational studies, was associated with increased mortality and lengths of stay. Interventions targeting early sedation depth assessment, starting in the emergency department and subsequent ICU admission, deserve further investigation and could improve outcome.
No takes yet. Share an insight, caveat, or question.
Stephens et al. (2017) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: