Does cardiac resident macrophage-derived legumain improve cardiac repair after myocardial infarction?
Cardiac resident macrophage-derived legumain plays a crucial role in cardiac repair post-myocardial infarction by promoting efferocytosis and resolving acute inflammation.
Our results directly link efferocytosis to wound healing in the heart and identify Lgmn as a significant link between acute inflammation resolution and organ function.
Jia et al. (Mon,) studied this question.