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September 21, 2006New England Journal of MedicineOpen Access

The Complement Inhibitor Eculizumab in Paroxysmal Nocturnal Hemoglobinuria

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PHPeter HillmenNYNeal S. YoungJSJörg Schubert

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Hillmen et al. (2006) studied this question.

synapsesocial.com/papers/69dac59eaae38ff6ad8369a2https://doi.org/10.1056/nejmoa061648
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inherited Complete Deficiency of 20-Kilodalton Homologous Restriction Factor (CD59) as a Cause of Paroxysmal Nocturnal Hemoglobinuria1990 · 362 citations
  2. 2Fatigue in cancer patients compared with fatigue in the general United States population2002 · 854 citations
  3. 3Complement-induced vesiculation and exposure of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria1993 · 226 citations
  4. 4Regulatory control of complement on blood platelets1989 · 102 citations
  5. 5Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria.1989 · 412 citations