Squamous Cell Carcinoma of the Prostate: Report of 2 Cases and Review of the Literature

Two cases of squamous cell carcinoma of the prostate are reported and criteria for diagnosis are suggested. Squamous cancer, which accounts for 0.5 to 1% of prostatic malignancies, differs from the common adenocarcinoma of the prostate in certain clinical features. It also appears to have a worse prognosis and to be unresponsive to the usual therapies for prostatic cancer, perhaps because of a different cell of origin.