What question did this study set out to answer?

To measure and characterize the baseline concentrations and temporal variations of ammonia, acetone, and propanol in human breath using selected ion flow tube mass spectrometry.

February 14, 2006Physiological Measurement

A longitudinal study of ammonia, acetone and propanol in the exhaled breath of 30 subjects using selected ion flow tube mass spectrometry, SIFT-MS

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Authors

CTClaire TurnerBreast Cancer Now PŠPatrik ŠpanělCzech Academy of Sciences, J. Heyrovský Institute of Physical Chemistry DSDavid SmithUniversity of Essex

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Implication

Longitudinal study reveals log-normal distributions of breath volatile compounds in healthy volunteers, indicating SIFT-MS utility for non-invasive health monitoring.

Key Points

To measure and characterize the baseline concentrations and temporal variations of ammonia, acetone, and propanol in human breath using selected ion flow tube mass spectrometry.
Tracked 30 healthy volunteers (19 males, 11 females) over a 6-month longitudinal period.
Collected breath samples weekly before lunch between 8:45 am and 1:00 pm, quantifying trace volatile compounds with selected ion flow tube mass spectrometry (SIFT-MS).
Concentrations followed log-normal distributions, with geometric means of 833 ppb for ammonia (range 248–2935 ppb, multiplicative SD 1.62) and 477 ppb for acetone (range 148–2744 ppb, multiplicative SD 1.58), while median propanol was 18 ppb (range 0–135 ppb).
Breath ammonia levels increased significantly with subject age, and a weak but statistically significant correlation emerged between exhaled propanol and acetone.

Cite This Study

Turner et al. (2006) studied this question.

synapsesocial.com/papers/69daccd88988aeabbe687c41 https://doi.org/10.1088/0967-3334/27/4/001

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Implication

Longitudinal study reveals log-normal distributions of breath volatile compounds in healthy volunteers, indicating SIFT-MS utility for non-invasive health monitoring.

A longitudinal study of ammonia, acetone and propanol in the exhaled breath of 30 subjects using selected ion flow tube mass spectrometry, SIFT-MS

Discussion

Member takes

Implication

Key Points

Cite This Study

A longitudinal study of ammonia, acetone and propanol in the exhaled breath of 30 subjects using selected ion flow tube mass spectrometry, SIFT-MS

Discussion

Member takes

Implication

Key Points

Cite This Study

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