Why the study?
Does losartan reduce aortic dilatation rate in adults with Marfan syndrome?
Population
Adults with Marfan syndrome
Design
RCT, randomized
Authors
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Supports losartan to slow aortic dilatation in Marfan syndrome; extends evidence to arch dilatation after root replacement.
Does losartan reduce aortic dilatation rate in adults with Marfan syndrome?
Losartan effectively reduces the rate of aortic root and arch dilatation in adult patients with Marfan syndrome.
Groenink et al. (2013) studied this question.
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