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September 14, 2022Frontiers in Public HealthOpen Access

Persistently high incidence rates of childhood acute leukemias from 2010 to 2017 in Mexico City: A population study from the MIGICCL

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Authors

JFJanet Flores‐LujanoMexican Social Security InstituteDDDavid Aldebarán Duarte-RodríguezMexican Social Security InstituteEJElva Jiménez‐HernándezHospital Pediátrico Moctezuma

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Implication

Population study reveals persistently high childhood acute leukemia incidence and municipal spatial heterogeneity, suggesting combined genetic and environmental risk factors.

Key Points

  • To evaluate longitudinal incidence trends and spatial distribution patterns of childhood acute leukemia across urban municipalities.
  • Analyzed population-based cancer registry data from the MIGICCL covering children diagnosed between 2010 and 2017 in Mexico City.
  • Calculated world age-standardized incidence rates (ASIRw) and assessed spatial rate variation across municipal districts.
  • Childhood acute leukemia incidence rates remained among the highest recorded internationally throughout the 2010–2017 period.
  • Statistically significant spatial heterogeneity in acute leukemia incidence was observed across municipal boundaries.

Cite This Study

Flores‐Lujano et al. (2022) studied this question.

synapsesocial.com/papers/69dadcb94e9a02dbaa684bb9https://doi.org/10.3389/fpubh.2022.918921
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