Why the study?
Does dietary capsaicin trigger browning of white adipose tissue to counteract obesity?
Does dietary capsaicin trigger browning of white adipose tissue to counteract obesity?
Dietary capsaicin may counter obesity by activating TRPV1 channels to induce browning of white adipose tissue.
May support human trials of dietary capsaicin for obesity; leaves open translation from this animal TRPV1 study.
Our results show for the first time that activation of TRPV1 channels by dietary capsaicin triggers browning of WAT to counteract obesity. Our results suggest that activation of TRPV1 channels is a promising strategy to counter obesity.
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Baskaran et al. (2016) studied this question.
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