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September 22, 2023Journal of Neonatal-Perinatal Medicine

Safety evaluation of the use of calcineurin inhibitor to prenatal and postpartum women in Japan from a health administrative database

Kazuo Yashima Akira Noda Tomofumi Ishikawa Fumio Matsuzaki Keiko Miyakoda Hidekazu Nishigori Nariyasu Mano Taku Obara

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Abstract

No congenital anomalies were clearly attributable to the use of CNIs during pregnancy.

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Yashima et al. (2023) studied this question.

synapsesocial.com/papers/69dae34778a3e0e28868497d https://doi.org/10.3233/npm-230138

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Pregnancy and neonatal outcomes in women receiving calcineurin inhibitors: A systematic review and meta‐analysismeta-analysis · 2022 · 28 citations
2Calcineurin inhibitors experience in unplanned pregnancies with active lupus disease: A retrospective observational study2024 · 4 citations
3Comparison of pregnancy outcomes in Dutch kidney recipients with and without calcineurin inhibitor exposure: a retrospective studycohort · 2021 · 12 citations
4Calcineurin inhibitors and the risk of preeclampsia in solid organ transplantation – Should we rethink our approach during pregnancy?review · 2026
5Kidney adverse events associated with calcineurin inhibitors: a real-world study based on the FAERS database and network pharmacologyOriginal Research · 2026 · 2 citations

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Efficacy and safety of calcineurin inhibitors (CNIs) for septic patients in ICU: a cohort study from MIMIC database2024
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Immune Checkpoint Inhibitor Use During Pregnancy and Outcomes in Pregnant Individuals and Newborns2024

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