The Role of Lysosomes in Inflammation and Disease

Therefore, this review will limit it­ self to three aspects of this rapidly enlarging field: (a) Iysosomes in tissue injury and inflammation; (b) Iysosomes in immunopathology; and (c) Iyso­ somes in human disease. Lysosomes comprise a heterogeneous group of cyt oplasmic organelles, the ultrastructural appearance of which in tissues depends upon the history of the particle (5). Lysosomes which have not participated in acts of diges tion arc called primary lysosomes, the storage-granule form of which is exempli­