The study reveals a sex-specific decline in brown adipose tissue activity and its impact on adiposity with aging, with males experiencing a much stronger decline than females.
Our data corroborate that, in general, BAT activity and BAT mass are elevated in female subjects and in younger people. Importantly, we provide novel evidence that the impact of BAT activity and BAT mass on adiposity appears to decline with aging only in male subjects. Furthermore, while BAT activity and BAT mass only moderately decline with increasing age in female subjects, a much stronger effect is found in male subjects.
Pfannenberg et al. (Thu,) studied this question.