Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China

Iona Y. Millwood; Robin Walters; Xue W. Mei; Canqing Yu; Ling Yang; Zheng Bian; Derrick Bennett; Yiping Chen; Caixia Dong; Ruying Hu; Gang Zhou; Bo Yu; Weifang Jia; Sarah Parish; Robert Clarke; George Davey Smith; Rory Collins; Michael V. Holmes; Liming Li; Richard Peto; Zhengming Chen

doi:10.1016/s0140-6736(18)31772-0

Key Points

To explore the relationship between alcohol consumption and the aetiology of vascular diseases using both conventional and genetic evidence.
Prospective study design involving 500,000 men and women in China.
Data collected on alcohol consumption and vascular disease outcomes.
Analysis included genetic evidence related to vascular disease risk.
Findings suggest a significant association between alcohol consumption and increased risk of vascular diseases.
The genetic analysis provides further support for the relationship, indicating potential pathways of influence.

Implication

Prospective study examines the link between alcohol and vascular disease in a large population, suggesting important implications for health.

Abstract

Chinese Ministry of Science and Technology, Kadoorie Charitable Foundation, National Natural Science Foundation of China, British Heart Foundation, Cancer Research UK, GlaxoSmithKline, Medical Research Council, and Wellcome Trust.

Discussion

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Cite This Study

Millwood et al. (2019) studied this question.

synapsesocial.com/papers/69db11430d8d6ef495a3cb6b https://doi.org/10.1016/s0140-6736(18)31772-0

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Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China

Key Points

Implication

Abstract

Discussion

Cite This Study

Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China

Key Points

Implication

Abstract

Discussion

Cite This Study

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