Why the study?
Does pulsed field ablation reduce pulmonary vein narrowing compared to thermal ablation?
Does pulsed field ablation reduce pulmonary vein narrowing compared to thermal ablation?
In the first randomized comparison, pulsed field ablation demonstrated a more favorable safety profile regarding pulmonary vein tissue by resulting in less PV narrowing than thermal ablation.
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May favor PFA selection to limit PV narrowing risk; provides first RCT evidence of differential tissue effects versus thermal ablation.
In this first randomized comparison of PFA vs. thermal ablation, PFA resulted in less PV narrowing-thereby underscoring the qualitatively differential and favourable impact of PFA on PV tissue.
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Mansour et al. (2024) studied this question.
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