Answers are grounded in this paper and cite their sources.
Nirogacestat was associated with significant benefits with respect to progression-free survival, objective response, pain, symptom burden, physical functioning, role functioning, and health-related quality of life in adults with progressing desmoid tumors. Adverse events with nirogacestat were frequent but mostly low grade. (Funded by SpringWorks Therapeutics; DeFi ClinicalTrials.gov number, NCT03785964.).
No takes yet. Share an insight, caveat, or question.
Gounder et al. (2023) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: