Why the study?
Does increased endogenous thrombin potential predict the risk of first or recurrent deep venous thrombosis?
Population
360 patients and 404 control subjects from the Leiden Thrombophilia Study
Comparison
Increased endogenous thrombin potential > 90th… vs Normal endogenous thrombin potential
Design
Case-control
Authors
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Increased ETP may associate with first DVT risk; leaves open predictive utility for recurrence or clinical decisions.
Does increased endogenous thrombin potential predict the risk of first or recurrent deep venous thrombosis?
High endogenous thrombin potential is associated with an increased risk of a first deep venous thrombosis, particularly idiopathic, but does not predict recurrent venous thrombosis.
Vlieg et al. (2007) studied this question.
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