Why the study?
Does resumption of anticoagulation reduce recurrent venous thromboembolism in patients with an abnormal D-dimer level 1 month after the discontinuation of anticoagulation?
Does resumption of anticoagulation reduce recurrent venous thromboembolism in patients with an abnormal D-dimer level 1 month after the discontinuation of anticoagulation?
Resumption of anticoagulation reduces recurrent venous thromboembolism in patients with abnormal D-dimer levels 1 month post-discontinuation.
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May support resuming anticoagulation for abnormal D-dimer to reduce recurrent VTE; leaves open need for randomized confirmation.
Patients with an abnormal D-dimer level 1 month after the discontinuation of anticoagulation have a significant incidence of recurrent venous thromboembolism, which is reduced by the resumption of anticoagulation. The optimal course of anticoagulation in patients with a normal D-dimer level has not been clearly established. (ClinicalTrials.gov number, NCT00264277 [ClinicalTrials.gov].).
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Palareti et al. (2006) studied this question.
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