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This research aims to explore the evolutionary history and classification of olfactory receptor genes in humans.

Evolution of olfactory receptor genes in the human genome

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This research aims to explore the evolutionary history and classification of olfactory receptor genes in humans.
Identified complete set of olfactory receptor genes and chromosomal locations from human genome sequences.
Conducted phylogenetic analysis to classify genes into subclasses and clades.
Analyzed the relationship between genomic clusters and phylogenetic clades.
Identified 388 potentially functional olfactory receptor genes and 414 pseudogenes.
Class II olfactory receptor genes classified into 19 phylogenetic clades with high support values.
Documented complex relationships between genomic clusters and phylogenetic clades due to chromosomal rearrangements.

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Randomized trial investigates olfactory receptor gene evolution, indicating complex rearrangements in humans.

Niimura et al. (2003) studied this question.

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