Why the study?
Is SDMA a marker of estimated GFR and CAD extent, and does it affect endothelial NO synthesis?
Population
97 patients with coronary artery disease (CAD) and cultured endothelial cells
Design
Other
Authors
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SDMA may mark cardiorenal risk in CAD; leaves open causal endothelial effects pending prospective validation.
Is SDMA a marker of estimated GFR and CAD extent, and does it affect endothelial NO synthesis?
SDMA may serve as a useful biomarker for early detection of chronic kidney disease and cardiovascular risk, potentially by limiting L-arginine supply to NOS and reducing endothelial NO synthesis.
Bode‐Böger et al. (2006) studied this question.
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