Why the study?
Do acetylcholine and substance P require an intact endothelium to elicit vasodilatation in vivo in the canine femoral artery?
Population
Anaesthetized dogs (canine femoral artery in vivo)
Comparison
Acetylcholine and substance P administered… vs Arteries with endothelium removed by mechanical…
Design
Preclinical
Authors
Loading...
Demonstrates endothelium-dependent vasodilatation in vivo in canines; leaves open translation to human vascular physiology and therapy.
Do acetylcholine and substance P require an intact endothelium to elicit vasodilatation in vivo in the canine femoral artery?
Acetylcholine and substance P require an intact endothelium to elicit vasodilatation in vivo in the canine femoral artery.
Angus et al. (1983) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: