Why the study?
Do therapies such as fluorinated steroids, beta-agonists, IVIG, and hydroxychloroquine improve outcomes in fetuses with or at risk for autoimmune-associated congenital heart block?
Do therapies such as fluorinated steroids, beta-agonists, IVIG, and hydroxychloroquine improve outcomes in fetuses with or at risk for autoimmune-associated congenital heart block?
This review highlights that while no therapies permanently reverse third-degree congenital heart block, treatments like fluorinated steroids, IVIG, and hydroxychloroquine may offer benefits in incomplete block, cardiomyopathy, or prevention.
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No therapies permanently reverse third-degree block; leaves open possible adjunctive roles for steroids and IVIG in incomplete cases.
Saxena et al. (2014) studied this question.
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