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March 31, 2026Journal of Veterinary and Animal SciencesOpen Access

Haemato-biochemical and blood gas changes in cattle under multimodal general anaesthesia using guaiphenesin-ketamineisoflurane with butorphanol-xylazine-ketamine premedication

Riya Jose Syam K. Venugopal S. Anoop Reji Varghese Soumya Ramankutty K. Karthiayini

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Key Points

The aim is to evaluate haemato-biochemical and blood gas alterations during multimodal general anaesthesia in cattle.
Conducted on six female cattle of different breeds, aged 6 months to 10 years.
Pre-anaesthetic sedation using butorphanol, xylazine, and ketamine.
Anaesthesia induced with a ketamine-guaiphenesin double drip and maintained using isoflurane.
Significant leukopenia observed post induction of anaesthesia.
No notable changes in total erythrocyte count or haemoglobin concentration during maintenance.
Mild fluctuations in aspartate aminotransferase and significant reduction in alanine aminotransferase levels recorded.

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Implication

Assesses blood gas alterations in cattle under multimodal general anaesthesia, indicating important physiological changes.

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Cite This Study

Jose et al. (2026) studied this question.

synapsesocial.com/papers/69db35be4fe01fead37c43c4 https://doi.org/10.51966/jvas.2026.57.1.133-139

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