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To investigate haemato-biochemical changes associated with clinical leptospirosis in dogs.

Haemato-biochemical alterations of clinical leptospirosis in dogs

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To investigate haemato-biochemical changes associated with clinical leptospirosis in dogs.
Collected blood and serum samples from 65 dogs showing clinical signs of leptospirosis.
Confirmed leptospirosis in 21 dogs using real-time PCR.
Analyzed haematological parameters and serum biochemical markers.
Positive dogs showed leucocytosis, neutrophilia, monocytosis, lymphocytosis, and thrombocytopenia.
Lower levels of haemoglobin, haematocrit, and total RBC count were observed.
Increased serum levels of alkaline phosphatase, albumin, bilirubin, creatinine, and blood urea nitrogen were noted.

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Blood and serum analyses demonstrate disease indicators in dogs with leptospirosis, suggesting future diagnostic approaches.

Wilson et al. (2026) studied this question.

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