Analysis reveals familial substance use history predicts earlier substance use in youth with externalizing disorders, indicating the need for targeted interventions.
Although there is considerable support for an externalizing behavioral phenotype in youth as a driver toward adolescent substance use, this predictive association was found to manifest only in the context of familial-SUD history. Familial SUD status may warrant particular consideration in the identification of and intervention with youth at risk for SUDs. (PsycInfo Database Record (c) 2026 APA, all rights reserved).
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