Key result
Isolated interatrial septal aneurysm linked to recurrent syncope and AVNRT in a two-year-old male.
Why the study?
Interatrial septal aneurysm persistence into childhood is rare and associated with increased risks of arrhythmias and embolic events.
Case Report (n=1)
No
This case highlights that interatrial septal aneurysms can persist into childhood and may be associated with arrhythmogenic complications like AV nodal re-entry tachycardia.
Prompts consideration of interatrial septal aneurysm in pediatric AVNRT; hypothesis-generating for its persistence and arrhythmogenic role in childhood.
Interatrial septal aneurysm (IASA) is not uncommon in fetal and neonatal screening echocardiography. However, its persistence into childhood is rare. The presence of an IASA was associated with increased risk of arrhythmias and embolic events. Fetal tachycardia was suspected at 34 weeks of gestational age. Fetal echocardiography showed a large IASA with a normal fetal heart rate and no other congenital abnormalities. The case presented again at the age of two years with recurrent syncopal attacks, with confirmed atrioventricular (AV) nodal re-entry tachycardia correlated with the symptoms. Echocardiography showed a large type R1 IASA. The patient was referred to cardiac electrophysiology for further management. Persistence of interatrial aneurysms into childhood is rare. It can be associated with arrhythmogenic complications. A new class of classification of IASA dedicated to fetal diagnosis is suggested.
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Taha et al. (2026) conducted a case report in Interatrial septal aneurysm with arrhythmia (n=1). Echocardiography and Holter monitoring was evaluated. An isolated interatrial septal aneurysm detected prenatally persisted into childhood and caused recurrent syncopal attacks and atrioventricular nodal re-entry tachycardia in a two-year-old male.
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