A case report finds coexisting sarcoid reaction and sarcoidosis needing differentiation from PDAC recurrence, suggesting diagnostic challenges.
INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) is one of the most severe malignant tumors. The recurrence rate is high, even after radical surgery. A sarcoid reaction is a histological finding that occurs in the lymph nodes in response to malignant tumors, infections, or foreign substances. Its histopathology is similar to that of sarcoidosis. Here, we report a case of coexisting sarcoid reaction and sarcoidosis that required differentiation from PDAC recurrence.
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Horie et al. (2026) studied this question.
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