Long-term outcomes of switching to BIC/FTC/TAF with or without prior INSTI experience: real-life data from a monocentric cohort of ART-experienced people with HIV

Antonio Cianciaruso; Nicola Colavito; Flavia Balena; Nicolò De Gennaro; Deborah Fiordelisi; Francesco Di Gennaro; Mariacristina Poliseno; Annalisa Saracino

doi:10.1080/03007995.2026.2651786

April 9, 2026Current Medical Research and Opinion

Long-term outcomes of switching to BIC/FTC/TAF with or without prior INSTI experience: real-life data from a monocentric cohort of ART-experienced people with HIV

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Key Points

The aim is to assess the long-term outcomes of switching to BIC/FTC/TAF in ART-experienced individuals with or without INSTI experience.
Monocentric cohort study design
Sample of ART-experienced individuals
Evaluation of switch outcomes over time
Assessment of safety and lipid profiles
BIC/FTC/TAF demonstrated durable efficacy and safety
The regimen was well tolerated by individuals without prior INSTI experience
Results indicate favorable lipid profiles when switching to BIC/FTC/TAF

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Implication

Real-life data demonstrate safety and effectiveness of ART switch in HIV-positive individuals, suggesting broad applicability.

Abstract

Our real-life data further support the role of BIC/FTC/TAF as a durable, safe and "lipid-friendly" ART switch option, also for PWH without prior INSTI experience.

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Cite This Study

Cianciaruso et al. (2026) studied this question.

synapsesocial.com/papers/69db36a04fe01fead37c49fa https://doi.org/10.1080/03007995.2026.2651786

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Long-term outcomes of switching to BIC/FTC/TAF with or without prior INSTI experience: real-life data from a monocentric cohort of ART-experienced people with HIV

Key Points

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Implication

Abstract

Discussion

Cite This Study

Long-term outcomes of switching to BIC/FTC/TAF with or without prior INSTI experience: real-life data from a monocentric cohort of ART-experienced people with HIV

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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