Tannic Acid and Copper-Modified ZIF-8 Metal Organic Framework as a Cefotaxime Delivery System for Antimicrobial Activity

Key Points

• The research explores the potential of ZIF-8 MOFs for targeted drug delivery of cefotaxime in infection treatment.
• Utilized ZIF-8 metal organic frameworks modified with tannic acid and copper.
• Examined release patterns of cefotaxime under varying pH conditions.
• Assessed antimicrobial activity of the drug delivery system.
• ZIF-8 MOFs demonstrated controlled release of cefotaxime in low pH environments.
• Potential antimicrobial effectiveness was observed with cefotaxime delivery.
• Demonstrated enhanced targeting ability for drug delivery systems in infection sites.