Non-decarboxylative functionalization of free carboxylic acids: Strategies for C–O bond formation via photo- and electrochemical approaches

Binbin Huang

doi:10.1039/d6gc00661b

January 1, 2026Green Chemistry

Non-decarboxylative functionalization of free carboxylic acids: Strategies for C–O bond formation via photo- and electrochemical approaches

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Key Points

The aim is to explore efficient methods for C–O bond formation using carboxylic acids through non-decarboxylative approaches.
Developed photo- and electrochemical techniques for C–O bond formation.
Investigated both electrophilic and nucleophilic reaction pathways.
Utilized readily available carboxylic acids as key starting materials.
Successfully achieved C–O bond formation with improved reactivity of carboxylic acids.
Demonstrated the effectiveness of photoelectrochemical strategies in organic synthesis.

Implication

Innovative methods for forming C–O bonds from carboxylic acids, suggesting broader applications in organic synthesis.

Abstract

Carboxylic acids are among the most readily available, bench-stable, and cost-effective building blocks in organic chemistry. However, the low reactivity of free carboxyl group in both electrophilic and nucleophilic transformations...

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Cite This Study

Binbin Huang (2026) studied this question.

synapsesocial.com/papers/69db36c24fe01fead37c4b0c https://doi.org/10.1039/d6gc00661b

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Non-decarboxylative functionalization of free carboxylic acids: Strategies for C–O bond formation via photo- and electrochemical approaches

Key Points

Implication

Abstract

Discussion

Cite This Study

Non-decarboxylative functionalization of free carboxylic acids: Strategies for C–O bond formation via photo- and electrochemical approaches

Key Points

Implication

Abstract

Discussion

Cite This Study

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