Impact of Intrahepatic Tumor Burden on Outcomes in Patients With Hepatocellular Carcinoma With Extrahepatic Metastases Treated With Atezolizumab Plus Bevacizumab

Key Points

• To investigate how intrahepatic tumor burden affects outcomes in patients with hepatocellular carcinoma and extrahepatic metastases.
• Analyzed patients with metastatic hepatocellular carcinoma
• Received treatment with atezolizumab and bevacizumab
• Evaluated overall survival related to intrahepatic tumor burden
• Intrahepatic tumor burden correlated with overall survival rates
• High tumor burden associated with poorer outcomes
• Findings may inform risk stratification and treatment optimization