A clinical case discusses advanced diagnostics for central nervous system infections, highlighting implications for practice.
A clinical case is presented to discuss a framework for use of advanced diagnostics for central nervous system infections. Advantages, limitations, and diagnostic stewardship strategies are discussed for each modality: multiplex molecular meningitis/encephalitis panel, plasma microbial cell-free DNA sequencing, and cerebrospinal fluid metagenomic next generation sequencing.
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Ryder et al. (2026) studied this question.
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