What question did this study set out to answer?

This research aims to assess a calibration method for heated tcPCO2 electrodes to improve accuracy in measuring Paco2 in sick newborns.

A Calibration Procedure for the Radiometer Heated Transcutaneous CO2 Electrode: Measurements in the Sick Newborn

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Calibration technique improves heated tcPCO2 accuracy in sick newborns, indicating better care protocols.

This research aims to assess a calibration method for heated tcPCO2 electrodes to improve accuracy in measuring Paco2 in sick newborns.
Used an in vivo correction factor for blood anaerobic heating coefficient and skin CO2 production.
Applied calibration technique during tcPCO2 monitoring of 16 sick infants in NICU.
Conducted regression analysis on 52 paired tcPCO2 and Paco2 measurements.
Found a close linear relationship between tcPCO2 and Paco2.
Predicted that tcPCO2 will be within 2 torr of Paco2 in most cases.
Concluded that in vivo calibration is preferable to in vitro methods.

Cohen et al. (1981) studied this question.

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