Risk Factors for Metastasis and Prognosis in Non‐Curative Resection After Endoscopic Submucosal Dissection for Undifferentiated‐Type Early Gastric Cancer in a Nationwide Cohort in Japan

Kazuo Shiotsuki; Kohei Takizawa; Akifumi Notsu; Waku Hatta; Hirotada Akiho; Masao Yoshida; Yusuke Horiuchi; Takashi Kanesaka; Seiichiro Abe; Masahiro Tajika; Yohei Furumoto; Osamu Dohi; S Shinzaki; Junichi Kodaira; Hiroyuki Hisada; Tomiki Sumiyoshi; Yosuke Toya; Takuya Wada; Jun Nakamura; Michiko Seo; Tomohiro Shimada; Aki Hasebe; Noriya Uedo; Hideki Ishikawa; Takuji Gotoda

doi:10.1111/den.70148

Key Points

The research aims to identify risk factors associated with lymph node metastasis in early gastric cancer following non-curative resection.
Analyzed data from a nationwide cohort in Japan
Examined lymphatic invasion and tumor size as primary factors
Utilized the eCura system for risk stratification
Lymphatic invasion significantly associated with increased risk of lymph node metastasis
Tumor size greater than 30 mm correlates with higher metastasis risk
Supports eCura system for improved risk assessment

Implication

Nationwide cohort study identifies risk factors for metastasis in undifferentiated-type early gastric cancer, suggesting improved patient outcomes.

Abstract

Lymphatic invasion and a tumor size > 30 mm are associated with the risk of LNM. Our findings support using the eCura system for risk stratification in undifferentiated-type EGC after non-curative resection.

Discussion

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Cite This Study

Shiotsuki et al. (2026) studied this question.

synapsesocial.com/papers/69db38534fe01fead37c6874 https://doi.org/10.1111/den.70148

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Risk Factors for Metastasis and Prognosis in Non‐Curative Resection After Endoscopic Submucosal Dissection for Undifferentiated‐Type Early Gastric Cancer in a Nationwide Cohort in Japan

Key Points

Implication

Abstract

Discussion

Cite This Study

Risk Factors for Metastasis and Prognosis in Non‐Curative Resection After Endoscopic Submucosal Dissection for Undifferentiated‐Type Early Gastric Cancer in a Nationwide Cohort in Japan

Key Points

Implication

Abstract

Discussion

Cite This Study

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