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January 23, 2012Hepatology

Histological diversity in cholangiocellular carcinoma reflects the different cholangiocyte phenotypes

Mina Komuta Olivier Govaere Vincent Vandecaveye Jun Akiba Werner Van Steenbergen Chris Verslype Wim Laleman Jacques Pirenne Raymond Aerts Hirohisa Yano Frederik Nevens Baki Topal Tania Roskams

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Abstract

Muc-ICCs had a clinicopathological, immunohistochemical, and molecular profile similar to that of hilar CCs (from mucin-producing cholangiocytes), whereas mixed-ICCs had a profile similar to that of CLCs (thought to be of HPC origin), possibly reflecting their respective cells of origin.

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Komuta et al. (2012) studied this question.

synapsesocial.com/papers/69db8bf7c9a120f055a3c0da https://doi.org/10.1002/hep.25595

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