Population
100 4-week-old cesarean-derived colostrum-deprived pigs
Comparison
Inoculation with US porcine reproductive and… vs Control group (uninoculated)
Design
Preclinical
Follow-up
at least 28 days
Authors
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Highlights isolate-dependent PRRSV pathogenesis in pigs; leaves open translation to field outbreaks or interventions.
The US PRRSV isolate VR2385 causes more severe disease and higher viral antigen loads in tissues compared to VR2431 and the European Lelystad virus in a pig model.
Halbur et al. (1995) studied this question.
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