Clinical practice guideline demonstrates consensus on metformin co-commencement to prevent antipsychotic-induced weight gain, highlighting evidence-based clinical implementation.
This is the first published evidence-based guideline using the AGREE II framework and GRADE methods for the use of metformin to prevent AIWG incorporating recommendations for co-commencement. Implementation and evaluation of the guideline will be supported by a shared decision-making package and assessment of barriers and facilitators to implementation.
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Carolan et al. (2024) studied this question.
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