What question did this study set out to answer?

Define and quantify specific endometrial histologic changes that correlate with microbiologically confirmed upper genital tract infection and laparoscopically diagnosed acute salpingitis.

February 1, 1990The American Journal of Surgical Pathology

Endometrial Histopathology in Patients with Culture-proved Upper Genital Tract Infection and Laparoscopically Diagnosed Acute Salpingitis

View Full Paper

Ask AI

Bookmark

Authors

NKNancy B. KiviatBoston University PWPål Wölner‐HanssenLouisiana State University DEDavid A. EschenbachUniversity of Washington

Discussion

Member takes

Implication

Observational study reveals that combined endometrial neutrophils and plasma cells identify acute salpingitis and infection in suspected PID, indicating biopsy is a reliable diagnostic tool.

Key Points

Define and quantify specific endometrial histologic changes that correlate with microbiologically confirmed upper genital tract infection and laparoscopically diagnosed acute salpingitis.
Analyzed endometrial biopsy specimens from 69 consecutive patients presenting with clinically suspected acute pelvic inflammatory disease.
Conducted upper genital tract microbiological cultures and diagnostic laparoscopy to evaluate for acute salpingitis in all participants.
Upper genital tract infection (UGTI) and acute salpingitis were both confirmed in 37 patients (54%), salpingitis alone in 11 (16%), UGTI alone in 1 (1%), and neither in 20 (29%).
Microbiological evaluation identified Chlamydia trachomatis or Neisseria gonorrhoeae in 34 patients, Escherichia coli in two, Peptococcus magnus in one, and Streptococcus agalactiae in one.
The simultaneous presence of ≥5 neutrophils per ×400 field in surface epithelium and ≥1 plasma cell per ×120 field in stroma yielded 92% sensitivity and 87% specificity for diagnosing UGTI and laparoscopically confirmed salpingitis.

Cite This Study

Kiviat et al. (1990) studied this question.

synapsesocial.com/papers/69dbb2fb498b35d3e6a3cf86 https://doi.org/10.1097/00000478-199002000-00008

View Full Paper

Ask AI

Bookmark

Implication

Observational study reveals that combined endometrial neutrophils and plasma cells identify acute salpingitis and infection in suspected PID, indicating biopsy is a reliable diagnostic tool.

Endometrial Histopathology in Patients with Culture-proved Upper Genital Tract Infection and Laparoscopically Diagnosed Acute Salpingitis

Discussion

Member takes

Implication

Key Points

Cite This Study

Endometrial Histopathology in Patients with Culture-proved Upper Genital Tract Infection and Laparoscopically Diagnosed Acute Salpingitis

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider