Why the study?
Does a sirolimus-eluting stent reduce restenosis and associated clinical events compared to standard stents in patients with stenosis in a native coronary artery?
Does a sirolimus-eluting stent reduce restenosis and associated clinical events compared to standard stents in patients with stenosis in a native coronary artery?
Sirolimus-eluting stents are effective at reducing restenosis and associated clinical events in patients with complex coronary lesions.
Supports first-line sirolimus-eluting stent use in native coronary stenosis; confirms consistent benefit across all subgroups.
In this randomized clinical trial involving patients with complex coronary lesions, the use of a sirolimus-eluting stent had a consistent treatment effect, reducing the rates of restenosis and associated clinical events in all subgroups analyzed.
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Moses et al. (2003) studied this question.
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